Carlson, G. L.; Li, B. U.; Bass, P.; Olsen, W. A.
JOURNAL NAME- Science
VOL. 219
NO. 4583
1983 Jan 28
PP. 393-5
DOCUMENT TYPE- Clinical Trial; Journal Article; Randomized Controlled Trial
JOURNAL CODE- 0404511
JOURNAL SUBSET- MEDJSIM
ISSN- 0036-8075
CONTRACT/GRANT NUMBER- 5P30 AM 26659.AM.NIADDK; AM 13927.AM.NIADDK; AM 21668.AM.NIADDK
PUBLICATION COUNTRY- UNITED STATES
LANGUAGE- English NDN- 240-0091-6441-0

A commercial alpha-amylase inhibitor with potent inhibitory activity in vitro was used in a randomized double-blind, cross-over clinical trial in six nonobese, healthy adult males. In these subjects, this inhibitor had no effect on the response of blood glucose, insulin, or breath hydrogen to a standardized starch meal. It is concluded that this formulation has no effect on starch digestion in humans.